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KMID : 1235520090080020161
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Research in Vestibular Science
2009 Volume.8 No. 2 p.161 ~ p.163
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Downbeat, Gaze-evoked and Perverted Head-shaking Nystagmus Associated with Dapsone Toxicity
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Kim Tae-Woo
Shin Byoung-Soo
Kim Young-Hyun
Oh Sun-Young
Seo Man-Wook
Choi Ha-Cheol
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Abstract
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Dapsone is an agent commonly used to treat leprosy and its most common adverse effect is a hemolytic anemia. We present a patient who showed transient downbeat, bilateral horizontal gaze-evoked nystagmus (GEN), and perverted head-shaking nystagmus after taking a large dose of dapsone. These oculomotor abnormalities are assumed to be a reversible vestibulocerebellar dysfunction caused by over-dose of dapsone.
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KEYWORD
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Downbeat nystagmus, Gaze-evoked nystagmus, Head-shaking nystagmus, Dapsone intoxication
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